Arriving by car

From the South Bay: Take 101 North to the Bay Bridge Exit on 4th Street. Cross 4th Street and stay in the 2 left-hand lanes. Turn left on to 3rd Street and then right onto Mission Street. Hotel Vitale is on your left on Mission Street. From the North Bay: Take 101 South across the Golden Gate Bridge Follow the signs for Downtown on Lombard Street. Turn right on Van Ness Avenue and make a left on Bush Street. Go approximately 2 miles and turn left onto Market Street. Continue 3 blocks until you reach a dead end at Steuart Street. Turn right onto Steuart Street and continue one block until you get to Mission Turn left and Hotel Vitale is located on your left. From the East Bay: Take I-80 towards the bay Bridge and exit on Fremont Street. Turn right on Mission Street and keep going until you get to the Embarcadero.Hotel Vitale is on your left.